• Automated Salt Deposition Monitor (ASDM)

    Insulator flashover happens when soluble and/or non-soluble contaminants cover the insulator surface which results in a reduction of the surface resistance [1]. FIA’s ASDM helps to predict the contamination level on the outdoor ceramic insulators surface. This can help as a mean to warn overhead lines operators about the advent of insulator flashover.

    The ASDM consists of an equipment with a pilot insulator exposed to the same condition as the operational insulators in a, e.g., converter station. Many stations are situated in demanding areas, typically close to a shore line. By frequently automatically monitoring the Equivalent Salt Deposit Density (ESDD) it helps the operators to understand the build-up of contaminants on the insulator surface. The ASDM also measures wind and wind direction, enabling it to give a prognosis of potential flash over conditions.

    The equipment is class IP64 and all outdoor parts are compatible with the demanding environment, such acid proof steel AISI 316, equivalent to corrosivity class C5-M.

    The user interface for monitoring and control may be positioned remotely in an adjacent building.

    The equipment is a modernized version of historical constructions installed at, e.g., nuclear power plants. FIA’s equipment has passed detailed technical reviews by demanding customers and our service team has passed the high security screens and made installations at restricted locations.

    Request a quote or send a line to i@fia.se and we can tell more.

    1. Abdelrahman K. Abouzeid, Ayman El-Hag & Khaled Assaleh (2018) Equivalent Salt Deposit Density Prediction of Silicone Rubber Insulators Under Simulated Pollution Conditions, Electric Power Components and Systems, 46:10, 1123-1133, DOI: 10.1080/15325008.2018.1488303

  • Andersen Blank Stage

    To achieve an even distribution of a dose from an OINDP on a filter for dissolution testing [1], a blank stage is introduced next to the filter stage on the Andersen impactor. The blank stage (lower part in the picture) fits to the ordinary Andersen stage (upper part in the picture).

    1. Sitaram P. Velagaa, Jelena Djuris, Sandra Cvijic, Stavroula Rozou, Paola Russo, Gaia Colombo Alessandra Rossi; European Journal of Pharmaceutical Sciences, ISSN: 0928-0987, Vol: 113, Page: 18-28

  • Automated Waste Station Turbuhaler/ICORes

    can be customised according to your device, the example shown here is for Turbuhaler/ICORes. The station can be made to withdraw doses in different angles, i.e., different orientation of the device, to overcome “memory effects” of reservoir inhalers. Actuation can be by push, pull or as shown here, with a twist. The doses are collected on a high-capacity filter, with a holding capacity of about 10 g. The disposable filter is then safely and easily replaced. The integration with FIA’s TriggerBox III gives the user full control of the flow process and relevant data recorded on file or printer. Can be equipped with anti-static-device. See here for more information.

  • This FIA product addresses the dynamics of testing dry-powder inhalers (DPIs). Compendial methods of testing DPIs call for an abrupt start and abrupt end to the air flow. An attribute aimed at representing the way a patient uses a DPI. The starting and stopping of the air flow introduces time-variant conditions in the test equipment (cascade impactor) and in the device itself. Experimental and computational studies of these conditions are continuing to elucidate the important characteristics of the device and test system that should be known and controlled to establish a sound quality control test for products that are or are about to be registered. FIA's latest instrument known as Stig puts in users hands the most important measure of the time-dependent air flow start-up the rise-time. It is important that the rise-time is known and under control when testing inhalable devices. Russell-Graham and colleagues1showed that the fine particle dose increases as the rise time decreases. Previous and subsequent theoretical analyses point out reasons for this effect.2, 3 For established products quality control (QC) testing requires knowing that the rise-time remains in a specified range...now possible with Stig. For GMP QC Stig can be locked to acquire and present the rise-time according to a defined and validated method. Since patients do generate different inhalation air-flow profiles it is also important during the development of a new drug product to adjust the prototype devices to exhibit a sensible rise-time close to what will take place in patient use. This mindset is equally important for DPIs and for breath-actuated MDI devices. Stig also makes possible the recording of air-flow profiles so that they can be reproduced on a breathing simulator (such as F-SIG 6300) for studying nebulizers. Versatile and user-friendly. Best-in-class - that is the new Stig from FIA.

    Key features of Stig Restricted Version:

    • Rise-time measurement 0.1-1 s using a thermal flow meter
    • Average rise-time from a series of measurements
    • Touch-screen which displays a graph of flow vs. time, rise-time and the final flow
    • Battery powered
    • Optional IQ/OQ and quality certificate for the regulated industry

    Download the pdf Rise-time Measurement Instrument Stig

    1. Russell-Graham, D., A. Cooper, B. Stobbs, E. McAulay, H. Bogard, V. Heith, E. Monsallier, "Further Evaluation of the Fast-Screening Impactor for Determining Fine-Particle Fraction of Dry Powder Inhalers, "Drug Delivery to the Lung, December 8 to 10, 2010, Edinburgh, Scotland.
    2. Roberts, D. L., M. Chiruta, "Transient Impactor Behavior during the Testing of Dry-Powder Inhalers via Compendial Methods, "Drug Delivery to the Lung 18, The Aerosol Society, Edinburgh, Scotland, December 13-14, 2007.
    3. Versteeg, H., P. Zhao, C. Blatchford, M. Copley, D. L. Roberts, J. P. Mitchell, "A Computational Fluid Dynamics (CFD) Model of the Start-Up Kinetics of the Andersen Cascade Impactor (ACI), "Drug Delivery to the Lung, Aerosol Society, Edinburgh, Scotland, December 9-11 2015; pages 18-21.

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